Rheumatology ICD-10 Codes & CPT Codes

Rheumatology covers autoimmune and inflammatory conditions of the joints, muscles, and connective tissue. Precise coding for rheumatoid arthritis, lupus, gout, and osteoporosis is critical for prior authorization and biologic drug approvals. This page covers the top ICD-10-CM and CPT codes used by rheumatologists across the United States.

FY 2026 ICD-10-CM (CMS) · CPT codes updated annually · All codes verified billable

Top ICD-10 Codes for Rheumatology

ICD-10 Code Description Billable
M06.9 Rheumatoid arthritis, unspecified
M05.79 Rheumatoid arthritis with rheumatoid factor of multiple sites
M32.9 Systemic lupus erythematosus, unspecified
M45.9 Ankylosing spondylitis of unspecified sites in spine
M34.9 Systemic sclerosis, unspecified (scleroderma)
M35.00 Sicca syndrome, unspecified (Sjogren’s syndrome)
M79.7 Fibromyalgia
M10.9 Gout, unspecified
M17.11 Primary osteoarthritis, right knee
M81.0 Age-related osteoporosis without current pathological fracture
M35.3 Polymyalgia rheumatica
M30.0 Polyarteritis nodosa
M35.9 Systemic involvement of connective tissue, unspecified
M15.9 Polyosteoarthritis, unspecified
M60.9 Myositis, unspecified

Source: CMS ICD-10-CM Official Code Set FY 2026

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Common CPT Codes for Rheumatology Billing

CPT Code Description
99213 Office visit, established patient, low complexity
99214 Office visit, established patient, moderate complexity
99215 Office visit, established patient, high complexity
20610 Arthrocentesis, aspiration and/or injection, major joint or bursa
77080 Dual-energy X-ray absorptiometry (DXA), bone density study, axial skeleton
96372 Therapeutic, prophylactic, or diagnostic injection; subcutaneous or intramuscular

CPT descriptions are editorial summaries. Refer to the CMS Physician Fee Schedule for official rates.

Rheumatology Billing & Coding Tips

  • M05.x (seropositive RA) and M06.x (other RA) differ by serology — M05 requires documented positive RF or anti-CCP; do not code M05.x without lab confirmation.
  • Gout codes (M10.x) require specifying the site and type (primary, lead-induced, drug-induced) — unspecified M10.9 will not support biologic authorization.
  • Add the drug adverse effect code (T36–T50) when coding drug-induced conditions such as drug-induced lupus or drug-induced gout.
  • Biologic drug prior authorization often requires ICD-10 codes with disease severity indicators — code active disease (not ‘in remission’) when the condition is currently being treated with biologics.

Frequently Asked Questions

What is the ICD-10 code for rheumatoid arthritis?

M06.9 is the unspecified code. For seropositive RA (positive RF or anti-CCP), use M05.x with the appropriate site. M06.0x is seronegative RA. Always code to the site and serology status documented in the chart for biologic drug authorization.

What is the code for fibromyalgia?

M79.7 is Fibromyalgia. It is a standalone billable code. CMS and most commercial payers accept it as a primary diagnosis. Documentation should include the ACR 2010 diagnostic criteria (widespread pain index and symptom severity scale scores).

What ICD-10 code is used for lupus?

M32.9 is systemic lupus erythematosus (SLE), unspecified. M32.10–M32.19 covers lupus with organ or system involvement. M32.0 is drug-induced SLE (add the causative drug code from T36–T50 as well).

What CPT code is used for a joint injection?

20610 covers aspiration and/or injection of a major joint (knee, hip, shoulder, ankle). 20605 is for intermediate joints. 20600 is for small joints. Use imaging guidance add-on codes (77002, 76942) when ultrasound or fluoroscopy is used.

How does OmniMD support rheumatology billing?

OmniMD’s Rheumatology EHR includes disease activity scoring tools (DAS28, CDAI, SLEDAI), biologic prior authorization documentation templates, and integrated lab tracking for RF, anti-CCP, ANA, and complement levels.

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